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von Willebrand factor and platelet count in ruptured abdominal aortic aneurysm repair.

Authors
  • Adam, D J
  • Haggart, P C
  • Ludlam, C A
  • Bradbury, A W
Type
Published Article
Journal
European Journal of Vascular and Endovascular Surgery
Publisher
Elsevier
Publication Date
Oct 01, 2003
Volume
26
Issue
4
Pages
412–417
Identifiers
PMID: 14512005
Source
Medline
License
Unknown

Abstract

these data demonstrate that EC activation, the acute phase protein response, operative blood loss and aortic clamp time all contribute to the peri-operative fall in PC in patients with ruptured AAA. The peri-operative fall in circulating levels of vWF and PC may represent consumption secondary to macro- and microvascular thrombus formation. The resultant procoagulant state may partly explain the association between low PC and poor outcome in ruptured AAA.

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