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[In vivo formation from rat milk proteins of a peptide inhibitor of gastric secretion].

Authors
Type
Published Article
Journal
Biulleten' eksperimental'noĭ biologii i meditsiny
Publication Date
Volume
94
Issue
8
Pages
64–66
Identifiers
PMID: 7126859
Source
Medline
License
Unknown

Abstract

A peptide fraction was isolated from the gastric content of 10-day-old suckling rats by Sephadex G-25 and G-10 chromatography. Intravenous injection of peptide (15 mg) had a powerful inhibitory action on gastric secretion of dogs with Pavlov pouches. It is assumed that this fraction is formed from rat casein and inhibits gastric secretion in the newborn, reducing rat milk proteolysis.

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