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In vivo detection of cortical plaques by MR imaging in patients with multiple sclerosis.

Authors
  • Bagnato, F1
  • Butman, J A
  • Gupta, S
  • Calabrese, M
  • Pezawas, L
  • Ohayon, J M
  • Tovar-Moll, F
  • Riva, M
  • Cao, M M
  • Talagala, S L
  • McFarland, H F
  • 1 Neuroimmunology Branch, NINDS, Warren G. Magnuson Clinical Center, NIH, Bethesda, MD 20892-1400, USA. [email protected]
Type
Published Article
Journal
AJNR. American journal of neuroradiology
Publication Date
Jan 01, 2006
Volume
27
Issue
10
Pages
2161–2167
Identifiers
PMID: 17110688
Source
Medline
License
Unknown

Abstract

Averaging multiple SPGRs created a single high SNR volume, allowing identification of cortical lesions. Because data were obtained monthly for 1 year, the average image does not account for transient lesion activity. However, for cortical lesions that remained stable during this time, the findings are valid in demonstrating the importance of high SNR images for detecting cortical brain abnormalities in MS.

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