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In Vitro, In Vivo and Ex Vivo Models for Peripheral Nerve Injury and Regeneration.

Authors
  • Li, Andrew1
  • Pereira, Clifford1
  • Hill, Elise Eleanor2
  • Vukcevich, Olivia3
  • Wang, Aijun2, 3, 4, 5
  • 1 Hand and Microsurgery, Division of Plastic Surgery, Department of Surgery, School of Medicine, University of California Davis, Sacramento, California, USA.
  • 2 Department of Surgery, School of Medicine, University of California Davis, Sacramento, California, USA.
  • 3 Department of Surgery, Surgical Bioengineering Laboratory, School of Medicine, University of California Davis, Sacamento, California, USA.
  • 4 Institute for Pediatric Regenerative Medicine, Shriners Hospitals for Children, Sacramento, California, USA.
  • 5 Department of Biomedical Engineering, University of California Davis, Davis, California, USA.
Type
Published Article
Journal
Current neuropharmacology
Publication Date
Jan 01, 2022
Volume
20
Issue
2
Pages
344–361
Identifiers
DOI: 10.2174/1570159X19666210407155543
PMID: 33827409
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

Peripheral Nerve Injuries (PNI) frequently occur secondary to traumatic injuries. Recovery from these injuries can be expectedly poor, especially in proximal injuries. In order to study and improve peripheral nerve regeneration, scientists rely on peripheral nerve models to identify and test therapeutic interventions. In this review, we discuss the best described and most commonly used peripheral nerve models that scientists have and continue to use to study peripheral nerve physiology and function. Copyright© Bentham Science Publishers; For any queries, please email at [email protected]

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