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In vitro and in vivo evaluation of the enhancing activity of glycyrrhizin on the intestinal absorption of drugs.

Authors
  • Imai, T
  • Sakai, M
  • Ohtake, H
  • Azuma, H
  • Otagiri, M
Type
Published Article
Journal
Pharmaceutical research
Publication Date
Jan 01, 1999
Volume
16
Issue
1
Pages
80–86
Identifiers
PMID: 9950283
Source
Medline
License
Unknown

Abstract

The in vivo enhancing-activity of Grz in the absorption of drugs is dependent on GA, a hydrolysis product of Grz resulting from the action of beta-glucuronidase in intestinal flora.

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