In vitro and in vivo evaluation of the enhancing activity of glycyrrhizin on the intestinal absorption of drugs.
- Authors
- Type
- Published Article
- Journal
- Pharmaceutical research
- Publication Date
- Jan 01, 1999
- Volume
- 16
- Issue
- 1
- Pages
- 80–86
- Identifiers
- PMID: 9950283
- Source
- Medline
- License
- Unknown
Abstract
The in vivo enhancing-activity of Grz in the absorption of drugs is dependent on GA, a hydrolysis product of Grz resulting from the action of beta-glucuronidase in intestinal flora.