In vitro and in vivo evaluation of the enhancing activity of glycyrrhizin on the intestinal absorption of drugs.

T Imai; M Sakai; H Ohtake; H Azuma; M Otagiri

In vitro and in vivo evaluation of the enhancing activity of glycyrrhizin on the intestinal absorption of drugs.

Authors

Imai, T
Sakai, M
Ohtake, H
Azuma, H
Otagiri, M

Type

Published Article

Journal

Pharmaceutical research

Publication Date

Jan 01, 1999

Volume

16

Issue

1

Pages

80–86

Identifiers

PMID: 9950283

Source

Medline

License

Unknown

Abstract

The in vivo enhancing-activity of Grz in the absorption of drugs is dependent on GA, a hydrolysis product of Grz resulting from the action of beta-glucuronidase in intestinal flora.

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. This record was last updated on 07/02/2016 and may not reflect the most current and accurate biomedical/scientific data available from NLM. The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/9950283

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