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In vitro and in vivo activity of a recombinant toxin, OLX-209, which targets the erbB-2 oncoprotein.

Authors
  • Fischer, P H
  • Bird, R E
  • Kasprzyk, P G
  • King, C R
  • Turner, N A
  • Pastan, I
  • Kihara, A
  • Batra, J
Type
Published Article
Journal
Advances in enzyme regulation
Publication Date
Jan 01, 1994
Volume
34
Pages
119–128
Identifiers
PMID: 7942269
Source
Medline
License
Unknown

Abstract

OLX-209 has readily measurable activity, is safe in experimental animals, and is efficacious in model systems. These results support the concept of OLX-209 and provide groundwork for further development of this oncoprotein targeted agent.

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