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Vitamin C improves endothelium-dependent vasodilation in patients with insulin-dependent diabetes mellitus.

Authors
  • Timimi, F K
  • Ting, H H
  • Haley, E A
  • Roddy, M A
  • Ganz, P
  • Creager, M A
Type
Published Article
Journal
Journal of the American College of Cardiology
Publisher
Elsevier
Publication Date
Mar 01, 1998
Volume
31
Issue
3
Pages
552–557
Identifiers
PMID: 9502634
Source
Medline
License
Unknown

Abstract

Vitamin C selectively restores the impaired endothelium-dependent vasodilation in the forearm resistance vessels of patients with insulin-dependent diabetes mellitus. These findings indicate that nitric oxide degradation by oxygen-derived free radicals contributes to abnormal vascular reactivity in humans with insulin-dependent diabetes mellitus.

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