The majority of patients rated the appearance and behaviour of the visitors in regard to several parameters as very positive. Thus, most patients found the conversation to be useful for their mental status and situation by reducing fears, building hope, courage, confidence, and the resulting suggestions for coping. However, disease-related stress, depression and health locus of control were found at 3 months after hospital discharge (T2) for the characteristics in patients with no evidence of a positive/salutogenetic effect of the visitor's conversation. The results of the study indicate that the opportunity to talk with members of self-help groups was considered helpful by cancer patients and should be offered in the future. A medium-term effect concerning the health outcome could not yet be demonstrated in this study. Further research projects on the importance of self-help groups in health-care research are necessary.