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Vinblastine, a chemotherapeutic drug, inhibits palmitoylation of tubulin in human leukemic lymphocytes.

Authors
  • 1
Type
Published Article
Journal
Chemotherapy
0009-3157
Publisher
S. Karger AG
Publication Date
Volume
53
Issue
1
Pages
51–58
Identifiers
PMID: 17202812
Source
Medline

Abstract

This study identifies a previously unknown mechanism of action of vinblastine, the depalmitoylation of tubulin, and suggests that depalmitoylation of tubulin may be a target for new chemotherapeutic drugs.

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