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VHL gene deletion and enhanced VEGF gene expression detected in the stromal cells of retinal angioma.

Authors
  • Chan, C C
  • Vortmeyer, A O
  • Chew, E Y
  • Green, W R
  • Matteson, D M
  • Shen, D F
  • Linehan, W M
  • Lubensky, I A
  • Zhuang, Z
Type
Published Article
Journal
Archives of Ophthalmology
Publisher
American Medical Association
Publication Date
May 01, 1999
Volume
117
Issue
5
Pages
625–630
Identifiers
PMID: 10326959
Source
Medline
License
Unknown

Abstract

These findings suggest that vacuolated "stromal" cells represent the true neoplastic component in retinal angioma. These cells express vascular endothelial growth factor and therefore may be responsible for abundant neovascularization of retinal angioma.

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