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Ventricular size, cognitive function and depression in patients with multiple sclerosis.

Authors
Type
Published Article
Journal
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques
Publication Date
Volume
19
Issue
3
Pages
352–356
Identifiers
PMID: 1393845
Source
Medline

Abstract

The purpose of this study was to explore further the hypothesis that changes in cognitive function may occur in the mild stages of multiple sclerosis (MS) by determining whether ventricular enlargement was related to cognitive function. Ten measures of ventricular size were made in a sample of 123 MS patients with mild disability and 60 well-matched healthy controls. In addition, sixteen tests of cognitive function and the Beck Depression Inventory were administered. For the MS group, there were significant correlations between the ventricular measures and cognitive performance but not for the normal controls. Scores on the Beck Depression Inventory were not correlated with either cognitive performance or ventricular enlargement. These findings suggest that for the MS group cognitive impairment was related to the disease process but not to the level of depression.

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