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[Vascular and obstetrical prognosis after hypertension during pregnancy: value of renal biopsy (author's transl)].

Authors
  • Beaufils, M
  • Delauche, M C
  • Morel-Maroger, L
  • Leroux-Robert, C
  • Richet, G
Type
Published Article
Journal
Annales de médecine interne
Publication Date
Jan 01, 1980
Volume
131
Issue
6
Pages
339–342
Identifiers
PMID: 7469236
Source
Medline
License
Unknown

Abstract

Renal biopsy was performed in 125 patients with severe hypertension during pregnancy. Three groups could be defined: I: normal kidney; II: vascular lesions; III: nephropathy. The histological appearance could not be suspected from clinical criteria (age, parity, symptoms, date of appearance). About 70% of the patients in groups I and II had permanent metabolic disorders (mainly hypercholesterolemia) and had a familial history of hypertension. Recurrence of hypertension during subsequent pregnancies occurred in 70% of cases, identical in groups I and II, and therefore impossible to predict by histological findings. Permanent hypertension developed in 47% of group II patients and 8% of group I (p < 0.001). The authors conclude that hypertension during pregnancy affects a sub-population genetically selected and that renal biopsy is of little value for predicting the prognosis in future pregnancies. The indications for renal biopsy are discussed.

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