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Vascular endothelial growth factor modulates matrix metalloproteinase-9 expression in asthma.

Authors
Type
Published Article
Journal
American Journal of Respiratory and Critical Care Medicine
1073-449X
Publisher
American Thoracic Society
Publication Date
Volume
174
Issue
2
Pages
161–170
Identifiers
PMID: 16645174
Source
Medline

Abstract

These results indicate that there is a close relationship between VEGF and MMP-9 expression and that inhibition of VEGF receptor down-regulates the expression of MMP-9. These findings suggest that VEGF signaling regulates MMP-9 expression and plays a critical role in initiation and maintenance of asthma.

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