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Vascular Anomalies: From a Clinicohistologic to a Genetic Framework.

Authors
  • Greene, Arin K1
  • Goss, Jeremy A
  • 1 Boston, Mass. From the Department of Plastic and Oral Surgery, Children's Hospital Boston, Harvard Medical School.
Type
Published Article
Journal
Plastic and reconstructive surgery
Publication Date
May 01, 2018
Volume
141
Issue
5
Identifiers
DOI: 10.1097/PRS.0000000000004294
PMID: 29697621
Source
Medline
License
Unknown

Abstract

Identification of somatic mutations in vascular anomalies is changing the paradigm by which lesions are diagnosed and understood. Mutations and their pathways are providing potential targets for the development of novel pharmacotherapy. In the future, vascular anomalies will be managed based on clinical characteristics and molecular pathophysiology.

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