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[Variations in parathormone serum levels during treatment of Paget's disease with calcitonin of human or salmon origin (author's transl)].

Authors
  • Heynen, G
  • Franchimont, P
  • Gaspar, S
  • Gysen, P
  • Kanis, J A
Type
Published Article
Journal
Annales d Endocrinologie
Publisher
Elsevier
Publication Date
Jan 01, 1981
Volume
42
Issue
3
Pages
265–275
Identifiers
PMID: 7316460
Source
Medline
License
Unknown

Abstract

Biological effects of increasing doses of human and salmon calcitonin (CT) have been studied in 17 patients suffering from Paget's disease of bone. Results show a dose response relationship on indirect indices of bone turn-over. The plateau phenomenon occurs with both CT and more rapidly with the lower dosage. There is also a transient increase in parathyroid activity during the period of time when bone turn-over is decreasing. Calciuretic effect was more pronounced with salmon than with human CT.

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