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Variations in the human olfactory receptor pathway.

Authors
Type
Published Article
Journal
Cellular and molecular life sciences : CMLS
Publication Date
Volume
63
Issue
13
Pages
1485–1493
Identifiers
PMID: 16732427
Source
Medline
License
Unknown

Abstract

Of all five senses, olfaction is the most complex molecular mechanism, as it comprises hundreds of receptor proteins enabling it to detect and discriminate thousands of odorants. Until lately, the understanding of this highly sophisticated sensory neuronal pathway has been rather sketchy. The sequencing of the human genome and the consequent advent of new genomic tools have opened new opportunities to better understand this multifaceted biological system. Here, we present the relevant progresses made in the last decade and highlight the possible genetic mechanisms of human olfactory variability.

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