We found that there are variations of the arterial supply of the duodenum and the pancreas in the domestic cat. In not a single cat does the cranial pancreatico-duodenal artery supply the whole descending duodenum. In 80% of our cases it supplies the cranial half, and in 20% of our cases only the cranial third of the descending duodenum. Only 48% of our cases is the caudal pancreaticoduodenal artery the first branch of the cranial mesenteric artery. But in 52% of our cases it is the second or even the third branch of the cranial mesenteric artery.