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Variation in hemostatic parameters after intra-arterial and intravenous administration of iodinated contrast media.

Authors
Type
Published Article
Journal
Investigative Radiology
0020-9996
Publisher
Ovid Technologies (Wolters Kluwer) - Lippincott Williams & Wilkins
Publication Date
Volume
27
Issue
12
Pages
1025–1030
Identifiers
PMID: 1473919
Source
Medline

Abstract

Both ionic and nonionic contrast media are able to interfere with the clotting/fibrinolytic system in the general circulation when they are administered to patients at the usual dosages. Ioxaglate shows more marked anticoagulant and thrombin-generating effects than iopamidol. The procedure (ie, arterial catheter versus intravenous infusion) seems to be more important than the category of contrast medium in conditioning the magnitude of these effects.

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