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Variants of asthma and chronic obstructive pulmonary disease genes and lung function decline in aging.

Authors
  • Poon, Audrey H
  • Houseman, E Andres
  • Ryan, Louise
  • Sparrow, David
  • Vokonas, Pantel S
  • Litonjua, Augusto A
Type
Published Article
Journal
The journals of gerontology. Series A, Biological sciences and medical sciences
Publication Date
Jul 01, 2014
Volume
69
Issue
7
Pages
907–913
Identifiers
DOI: 10.1093/gerona/glt179
PMID: 24253534
Source
Medline
Keywords
License
Unknown

Abstract

Our findings that genetic variants of genes involved in asthma and chronic obstructive pulmonary disease are associated with lung function decline in normal aging participants suggest that similar genetic mechanisms may underlie lung function decline in both disease and normal aging processes.

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