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Variable response to probiotics in two models of experimental colitis in rats.

Authors
  • Shibolet, Oren
  • Karmeli, Fanny
  • Eliakim, Rami
  • Swennen, Erwin
  • Brigidi, Patrizia
  • Gionchetti, Paulo
  • Campieri, Massimo
  • Morgenstern, Sara
  • Rachmilewitz, Daniel
Type
Published Article
Journal
Inflammatory bowel diseases
Publication Date
Nov 01, 2002
Volume
8
Issue
6
Pages
399–406
Identifiers
PMID: 12454615
Source
Medline
License
Unknown

Abstract

Both VSL#3 and LGG significantly ameliorated colitis induced by the sulfhydryl-blocker iodoacetamide, but had no effect on the immune-mediated DNBS-induced colitis. The results suggest a possible role for sulfhydryl compounds in the protective effect of probiotic bacteria, and support their use in patients with inflammatory bowel disease.

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