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Value of liver biopsy in sarcoidosis.

Authors
  • Hercules, H D
  • Bethlem, N M
Type
Published Article
Journal
Archives of pathology & laboratory medicine
Publication Date
Oct 01, 1984
Volume
108
Issue
10
Pages
831–834
Identifiers
PMID: 6548124
Source
Medline
License
Unknown

Abstract

A study of liver biopsy specimens was done for 28 patients with sarcoidosis. Epithelioid cell granulomas were found in 22 cases. Among the patients with granulomas, 13 had had fever and/or arthralgia; no such symptoms were observed among the patients who did not have granulomas. We believe that these symptoms constitute a good indication for performing a liver biopsy. Measurement of the concentration of the granulomas in the liver tissue suggests that the probability of false-negative results is very remote, making repetition of the biopsy unnecessary. The nonspecific lesions found in the liver progress to epithelioid cell granulomas in a similar way to that found within pulmonary alveoli.

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