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[Value of the expression of p21RAS, P53, Bcl-2 oncoproteins and Ki-67(MIB-1) antigen of cellular proliferation in the diagnosis and prognosis of thyroi].

Authors
Type
Published Article
Journal
Anales del sistema sanitario de Navarra
Publication Date
Volume
23
Issue
2
Pages
247–255
Identifiers
PMID: 12886309
Source
Medline
License
Unknown

Abstract

The differences in the proliferative rate between adenomas and follicular carcinomas can be of help in differential diagnosis. The p53 manifestation and the loss of the Bcl-2 expression are correlated with the histological redifferentiation process. An intense manifestation of p21 RAS in papillary carcinoma is correlated with tumoural progression.

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