Affordable Access

deepdyve-link deepdyve-link
Publisher Website

Valproate reduces spontaneous generalized spikes and waves but not photoparoxysmal reactions in patients with idiopathic generalized epilepsies.

Authors
Type
Published Article
Journal
Epilepsia
Publication Date
Volume
52
Issue
7
Pages
1297–1302
Identifiers
DOI: 10.1111/j.1528-1167.2011.03058.x
PMID: 21480883
Source
Medline
License
Unknown

Abstract

This study provides evidence that the effect of VPA on SWDs differs dependent on the types of SWDs. In the majority of patients, spontaneous SWDs and SWDs induced by hyperventilation disappeared, whereas the PPR mostly remained under VPA treatment. These results point to different pathogenetic mechanisms underlying the spontaneous and the evoked generalized epileptic activity in the EEG.

Statistics

Seen <100 times