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Validation of the Friedewald formula for the determination of low-density lipoprotein cholesterol in renal transplant recipients.

Authors
  • Balal, Mustafa1
  • Paydas, Saime
  • Inal, Tamer
  • Demir, Erkan
  • Kurt, Cemal
  • Sertdemir, Yasar
  • 1 Faculty of Medicine, Department of Nephrology, Cukurova University, Adana, Turkey. , (Turkey)
Type
Published Article
Journal
Renal Failure
Publisher
Informa UK (Taylor & Francis)
Publication Date
May 01, 2010
Volume
32
Issue
4
Pages
455–458
Identifiers
DOI: 10.3109/08860221003658266
PMID: 20446783
Source
Medline
License
Unknown

Abstract

The LDL-C can be calculated by the following formula: LDL-C = 8.018 + (0.99 x FF LDL-C). The coefficient of determination correlation (r) for this regression was 0.977, which indicates that the calculated LDL-C levels can be used in RTRs with TG lower than 400 mg/dL. mLDL-C was significantly higher than cLDL-C. We observed that difference between cLDL-C and mLDL-C levels were not affected by serum creatinine levels and usage of CNIs, sirolimus, everolimus, ACEI, and ARB in RTRs.

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