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VALENCE AND AFFINITY OF EQUINE NONPRECIPITATING ANTIBODY TO A HAPTENIC GROUP.

Authors
  • KLIMAN, N R
  • ROCKEY, J H
  • KARUSH, F
Type
Published Article
Journal
Science (New York, N.Y.)
Publication Date
Oct 16, 1964
Volume
146
Issue
3642
Pages
401–403
Identifiers
PMID: 14186463
Source
Medline
Keywords
License
Unknown

Abstract

A nonprecipitable antibody to a haptenic group has been purified from equine serum. It is a 7S beta2delta immunoglobulin with high affinity for the specific hapten and two binding sites per antibody molecule. These results rule out univalence and low affinity as explanations of the nonprecipitability of this antibody.

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