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[Vaginal contraception in 1982. Realities and perspectives (author's transl)].

Authors
  • Limouzin-lamothe, M A
Type
Published Article
Journal
Contraception, fertilité, sexualité
Publication Date
Nov 01, 1982
Volume
10
Issue
11
Pages
759–769
Identifiers
PMID: 12311810
Source
Medline
Keywords
License
Unknown

Abstract

In recent years, there has been a definite renewal of interest in vaginal contraception. Locally applied suppositories and creams contain surfactants such as benzalkonium chloride or phenyl-mercury nitrate which are powerful spermicidal drugs capable of achieving spermatolysis of previously immobilized spermatozoa. They are highly efficient spermicides as indicated by a Pearl's index close to 1.5, provided they are employed exactly as prescribed. Sponge-soaked spermicides remain active for 2 or 3 days which is a good palliative to the short-lived efficacy of other galenical preparations. Locally applied spermicides have the added advantage of possessing bactericidal properties and preventing M.S.T. Vaginal rings inhibit ovulation through a continuous release of progestogen with a strong antigonadotropic action. A number of different rings have been tested with varying degrees of success. When anovulation is actually obtained, it is frequently accompanied by hyperestrogeny, spotting, and amenorrhea. Furthermore, metabolic and in particular lipid disorders induced by progestogens cannot be avoided. (author's modified)

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