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Vaccines in pregnant women and research initiatives.

Authors
  • Healy, C Mary
Type
Published Article
Journal
Clinical Obstetrics & Gynecology
Publisher
Ovid Technologies (Wolters Kluwer) - Lippincott Williams & Wilkins
Publication Date
Jun 01, 2012
Volume
55
Issue
2
Pages
474–486
Identifiers
DOI: 10.1097/GRF.0b013e31824f3acb
PMID: 22510631
Source
Medline
License
Unknown

Abstract

Successful maternal immunization requires consideration of maternal and infant disease burden, biological factors affecting immune response and placental transport of antibodies, optimal timing of immunization, safety and acceptability. Tetanus, inactivated influenza and acellular pertussis vaccines are recommended during pregnancy; others are recommended when maternal risk of infection is high. The development of new conjugate vaccines for use in adults may reduce global maternal and infant disease burden. Maternal immunization against group B streptococcus is projected to be superior to current preventative strategies in decreasing disease. Further evaluation of maternal immunization strategies to prevent maternal and infant infections is needed.

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