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Uveitis reactivation following recombinant zoster vaccination

Authors
  • Richards, Paige J.1
  • Wingelaar, Maxwell J.1
  • Armbrust, Karen R.2, 3
  • Kopplin, Laura J.1
  • 1 University of Wisconsin Department of Ophthalmology and Visual Sciences, United States
  • 2 University of Minnesota, Department of Ophthalmology and Visual Neurosciences, United States
  • 3 Minneapolis Veterans Affairs Health Care System, Department of Ophthalmology, United States
Type
Published Article
Journal
American Journal of Ophthalmology Case Reports
Publisher
Elsevier
Publication Date
May 03, 2021
Volume
23
Identifiers
DOI: 10.1016/j.ajoc.2021.101115
PMID: 34041415
PMCID: PMC8141504
Source
PubMed Central
Keywords
Disciplines
  • Case Report
License
Unknown

Abstract

Purpose Describe three cases of uveitis reactivation following immunization with recombinant zoster vaccine (RZV). Observations One patient developed reactivation of previously controlled multifocal choroiditis within one week of receiving RZV, requiring treatment with systemic corticosteroids. Two patients with previously controlled anterior uveitis developed new anterior segment inflammation after RZV; both were treated with topical corticosteroids and systemic antiviral therapy. Conclusion and importance Uveitis recurrence is an infrequent but serious potential ocular side effect of recombinant zoster vaccination.

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