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Utilizing food effects to overcome challenges in delivery of lipophilic bioactives: structural design of medical and functional foods.

Authors
  • McClements, David Julian
Type
Published Article
Journal
Expert Opinion on Drug Delivery
Publisher
Informa UK (Taylor & Francis)
Publication Date
Dec 01, 2013
Volume
10
Issue
12
Pages
1621–1632
Identifiers
DOI: 10.1517/17425247.2013.837448
PMID: 24053714
Source
Medline
License
Unknown

Abstract

Food-based delivery systems can be used to improve the oral bioavailability of lipophilic bioactives. There are a number of potential advantages to delivering lipophilic bioactives using functional or medical foods: greater compliance than conventional delivery forms; increased bioavailability and efficacy; and reduced variability in biological effects. However, food matrices are structurally complex multicomponent materials and research is still needed to identify optimum structures and compositions for particular bioactives.

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