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Utility of Montreal Cognitive Assessment in Differentiating Dementia With Lewy Bodies From Alzheimer's Dementia.

Authors
  • Yamamoto, Erin1
  • Mourany, Lyla2
  • Colleran, Rosemary2
  • Whitman, Christine2
  • Tousi, Babak2
  • 1 1 Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, OH, USA.
  • 2 2 Lou Ruvo Center for Brain Health, Cleveland Clinic, Cleveland, OH, USA.
Type
Published Article
Journal
American journal of Alzheimer's disease and other dementias
Publication Date
Dec 01, 2017
Volume
32
Issue
8
Pages
468–471
Identifiers
DOI: 10.1177/1533317517725811
PMID: 28871793
Source
Medline
Keywords
License
Unknown

Abstract

Alzheimer's disease (AD) and dementia with Lewy bodies (DLB) are the 2 most common neurodegenerative dementias. Identification of patients with DLB is necessary to guide appropriate clinical management and medication trials. Patients with DLB are reported to perform poorly on tasks of visuospatial and executive function, compared to patients with AD who perform poorly on memory tasks. Using the Montreal Cognitive Assessment, we found that patients with DLB (n = 73) had statistically significant lower performance in clock drawing (visuospatial and executive function) and higher performance in delayed recall (memory) subscores compared to patients with AD (n = 57). This score pattern should raise suspicion for a DLB diagnosis at initial evaluation of patients with dementia.

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