[Usefulness of wide-range microbiological diagnostics proceedings in case of simultaneous infection with four herpesviruses after allogeneic haematopoietic stem cell transplantation--a case report].
- Authors
- Type
- Published Article
- Journal
- Medycyna doświadczalna i mikrobiologia
- Publication Date
- Jan 01, 2014
- Volume
- 66
- Issue
- 1
- Pages
- 23–28
- Identifiers
- PMID: 25007510
- Source
- Medline
- License
- Unknown
Abstract
DNA of HSV-1, VZV, HHV-6 and EBV in serum samples was detected using molecular biology techniques. Viral level of HSV-1 and VZV was constantly increasing despite routine applied oral acyclovir therapy. These findings underline the value of real-time PCR technique used in current therapeutic procedures and for monitoring of antiviral therapy with nucleoside analogs. We found that real-time PCR is a useful tool in detection and monitoring of disseminated herpesviral infection, especially for the detection of low-copy viraemia in clinical specimens.