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[Usefulness of wide-range microbiological diagnostics proceedings in case of simultaneous infection with four herpesviruses after allogeneic haematopoietic stem cell transplantation--a case report].

Authors
  • Dzieciatkowski, Tomasz
  • Przybylski, Maciej
  • Rusicka, Patrycja
  • Madry, Krzysztof
  • Boguradzki, Piotr
  • Marchel, Halina
  • Jedrzejczak, Wiesław W
  • Młynarczyk, Grazyna
Type
Published Article
Journal
Medycyna doświadczalna i mikrobiologia
Publication Date
Jan 01, 2014
Volume
66
Issue
1
Pages
23–28
Identifiers
PMID: 25007510
Source
Medline
License
Unknown

Abstract

DNA of HSV-1, VZV, HHV-6 and EBV in serum samples was detected using molecular biology techniques. Viral level of HSV-1 and VZV was constantly increasing despite routine applied oral acyclovir therapy. These findings underline the value of real-time PCR technique used in current therapeutic procedures and for monitoring of antiviral therapy with nucleoside analogs. We found that real-time PCR is a useful tool in detection and monitoring of disseminated herpesviral infection, especially for the detection of low-copy viraemia in clinical specimens.

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