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The use of impulse oscillometry for separate analysis of inspiratory and expiratory impedance parameters in horses: effects of sedation with xylazine.

Authors
  • Klein, C
  • Smith, H-J
  • Reinhold, P
Type
Published Article
Journal
Research in Veterinary Science
Publisher
Elsevier
Publication Date
Apr 01, 2006
Volume
80
Issue
2
Pages
201–208
Identifiers
PMID: 16098552
Source
Medline
License
Unknown

Abstract

(i) R(rs), X(rs) as well as Re(rs) and Xe(rs) revealed no significant influence of sedation. However, separate analysis of inspiration and expiration revealed a significant influence of sedation on all inspiratory impedance parameters. (ii) During the 24 min period after sedation, almost all inspiratory parameters were found significantly dependent on the time course of sedation whereas expiratory parameters Re10, Xe1, and Xe5 were not influenced. These results indicate that confounding factors due to sedation act mainly during inspiration. Muscle relaxation in upper airways due to xylazine is suspected to be the main cause of these phenomena.

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