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Use of cerebrospinal fluid amyloid-β and total tau protein to predict favorable surgical outcomes in patients with idiopathic normal pressure hydrocephalus.

Authors
  • Tarnaris, Andrew
  • Toma, Ahmed K
  • Chapman, Miles D
  • Keir, Geoff
  • Kitchen, Neil D
  • Watkins, Laurence D
Type
Published Article
Journal
Journal of Neurosurgery
Publisher
Journal of Neurosurgery Publishing Group
Publication Date
Jul 01, 2011
Volume
115
Issue
1
Pages
145–150
Identifiers
DOI: 10.3171/2011.2.JNS101316
PMID: 21438653
Source
Medline
License
Unknown

Abstract

In this pilot study a combination of Aβ(1-42) levels and total tau protein levels predicted favorable surgical outcomes at 6 months with adequate accuracy to be of clinical use. Further study in a larger group with longer follow-up is warranted.

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