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Use of bisphosphonates and the risk of osteonecrosis among cancer patients: a systemic review and meta-analysis of the observational studies.

Authors
  • Lee, Si-Huei
  • Chan, Rai-Chi
  • Chang, Shy-Shin
  • Tan, Yin-Ling
  • Chang, Kai-Hsiang
  • Lee, Matthew C
  • Chang, Huai-En
  • Lee, Chien-Chang
Type
Published Article
Journal
Supportive Care in Cancer
Publisher
Springer-Verlag
Publication Date
Feb 01, 2014
Volume
22
Issue
2
Pages
553–560
Identifiers
DOI: 10.1007/s00520-013-2017-y
PMID: 24203085
Source
Medline
License
Unknown

Abstract

The available evidence suggests that use of BPs in cancer patients is associated with a substantial risk for ONJ. Patients receiving IV BP are at the highest risk. It is important to assess oral health before initiating therapy and to avoid dental procedures during the active phase of intravenous BP therapy.

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