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Use of (64)Cu-labeled fibronectin domain with EGFR-overexpressing tumor xenograft: molecular imaging.

Authors
  • Hackel, Benjamin J
  • Kimura, Richard H
  • Gambhir, Sanjiv S
Type
Published Article
Journal
Radiology
Publisher
Radiological Society of North America
Publication Date
Apr 01, 2012
Volume
263
Issue
1
Pages
179–188
Identifiers
DOI: 10.1148/radiol.12111504
PMID: 22344401
Source
Medline
License
Unknown

Abstract

The stability, low background, and target-specific tumor uptake and retention of the engineered fibronectin domain make it a promising EGFR molecular imaging agent. More broadly, it validates the fibronectin domain as a potential scaffold for a generation of various molecular imaging agents.

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