During a two year study period, 6163 samples of urine among a total of 10366 miscellaneous samples received for culture, were analysed. Of these 1488 samples (24.15%) showed evidence of infection. In our study, E. Coli was found most frequently (61.40%) followed by Klebsiella (17.1%). The pattern of antibiotic sensitivity was analysed. Ciprofloxacin and Norfloxacin proved to be the most promising among the new generation of antibiotics. Results with Cloxacillin, Colistin and Lincomycin were found to be disappointing. The study serves to analyse the pattern of urinary infection in our setup and also dwells upon the emergence of strains resistant to even the newer antibiotics.