Urinary and renal interstitial concentrations of TNF-alpha increase prior to the rise in albuminuria in diabetic rats.
- Published Article
- Publication Date
Oct 01, 2003
We found an early rise in renal TNF-alpha levels after induction of diabetes with STZ, which precedes the rise in UAE by about 2 weeks. These findings suggest a possible contribution of TNF-alpha in the complicated pathogenic process resulting in microalbuminuria in diabetes.
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The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/12969138