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Urinary oestriol and serum activities of human placental lactogen and heat stable alkaline phosphatase as indicators of fetoplacental function.

Authors
  • Karjalainen, O
  • Stenman, U
  • Widholm, O
Type
Published Article
Journal
Annales chirurgiae et gynaecologiae Fenniae
Publication Date
Jan 01, 1975
Volume
64
Issue
1
Pages
50–54
Identifiers
PMID: 1155905
Source
Medline
License
Unknown

Abstract

The accuracy of urinary oestriol and serum levels of human placental lactogen (HPL) and heat stable alkaline phosphatase (HSAP) as indicators of feto-placental function was studied in 76 patients with high risk pregnancy. Feto-placental dysfunction was predicted correctly by plasma HPL in 80%, by urinary oestriol in 70%, by serum HSAP in 47%, and by the complementary use of HPL and oestriol in 90% of the cases. Normal fetoplacental function was predicted correctly by plasma HPL in 94%, by urinary oestriol in 96%, by serum HSAP in 80%, and by the complementary use of oestril and HPL in 100% of the patients. The probability of feto-placental dysfunction with a pathological value was 88% with urinary oestriol, 84% with plasma HPL and 100% with the parallel use of oestriol and HPL. A normal value assured undisturbed feto-placental function in 89% with urinary oestriol, in 92% with plasma HPL and in 96% with the parallel use of oestriol and HPL.

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