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Upregulation of AT1 receptor gene on activation of protein kinase Cbeta/nicotinamide adenine dinucleotide diphosphate oxidase/ERK1/2/c-fos signaling cascade mediates long-term pressor effect of angiotensin II in rostral ventrolateral medulla.

Authors
  • Chan, Samuel H H
  • Wang, Ling-Lin
  • Tseng, Huey-Ling
  • Chan, Julie Y H
Type
Published Article
Journal
Journal of Hypertension
Publisher
Ovid Technologies (Wolters Kluwer) - Lippincott Williams & Wilkins
Publication Date
Sep 01, 2007
Volume
25
Issue
9
Pages
1845–1861
Identifiers
PMID: 17762649
Source
Medline
License
Unknown

Abstract

We concluded that the PKCbeta/NADPH oxidase/ERK1/2/CREB/c-fos cascade represents a novel signaling cascade that mediates the long-term pressor effect induced by angiotensin II in the RVLM.

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