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Upper urothelial tumours and the Balkan nephropathy. Inference from the study of a family pedigree.

Authors
  • Radovanovic, Z
  • Velimirovic, D
  • Naumovic, T
Type
Published Article
Journal
European Journal of Cancer
Publisher
Elsevier
Publication Date
Mar 01, 1990
Volume
26
Issue
3
Pages
391–392
Identifiers
PMID: 2141498
Source
Medline
License
Unknown

Abstract

In an area heavily affected by both Balkan nephropathy (BN) and upper urothelial tumours (UUT), an outbreak of UUT (followed later by BN) affected at least four of five siblings. Their cousins developed BN in a high proportion but no one of them had any sign of UUT. It has been suggested that host factors determine the outcome of exposure to the same agent(s) responsible for both diseases.

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