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Update on nonoxynol-9 as vaginal spermicide.

Authors
  • Iyer, Vidya
  • Poddar, S S
Type
Published Article
Journal
The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception
Publication Date
Dec 01, 2008
Volume
13
Issue
4
Pages
339–350
Identifiers
DOI: 10.1080/13625180802263515
PMID: 19117251
Source
Medline
License
Unknown

Abstract

Nonoxynol-9 (N-9) is a typical surfactant. For more than 30 years that very property of N-9 has been successfully exploited for its spermicidal action. It is available as an over-the-counter, locally acting vaginal spermicide. The suitability of N-9 as a spermicide is elaborated in this article. The reasons why N-9 may fail as a contraceptive are discussed. In spite of many drawbacks, which are mentioned in the article, N-9 is still often resorted to as a locally acting contraceptive. The review ends with suggestions to alter the molecular structure of N-9 and to adjust the dosages.

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