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Update on the adaptive immune responses of the dental pulp.

Authors
  • Hahn, Chin-Lo
  • Liewehr, Frederick R
Type
Published Article
Journal
Journal of Endodontics
Publisher
Elsevier
Publication Date
Jul 01, 2007
Volume
33
Issue
7
Pages
773–781
Identifiers
PMID: 17804311
Source
Medline
License
Unknown

Abstract

Recent advances in immunology have disclosed the enormous complexity of the immune regulatory system. The dental pulp is equipped to mount adaptive immune responses to caries, which include at least antigen-presenting cells, lymphocytes, mast cells and their cytokines, and chemokines. The purpose of this review is to summarize our current understanding of the roles of these cellular and molecular components in the irreversibly inflamed pulp. The immunopathology of abscess formation and the mechanisms for painless pulpitis are also discussed.

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