Unmasking connections in transmembrane immune signaling
- Authors
- Type
- Published Article
- Journal
- Nature Immunology
- Publisher
- Springer Nature
- Publication Date
- Oct 01, 2004
- Volume
- 5
- Issue
- 10
- Pages
- 1008–1010
- Identifiers
- DOI: 10.1038/ni1004-1008
- Source
- Springer Nature
- License
- Yellow
Abstract
The B cell transmembrane glycoprotein modulates immune signaling. Mice containing specific Cd22 mutations show that the extracellular glycan-binding function is regulatory and indicate unexpected complexity in CD22-ligand interactions.