Affordable Access

The Unique Mechanisms of Cellular Proliferation, Migration and Apoptosis are Regulated through Oocyte Maturational Development—A Complete Transcriptomic and Histochemical Study

Authors
  • chermuła, błażej
  • brązert, maciej
  • jeseta, michal
  • ożegowska, katarzyna
  • sujka-kordowska, patrycja
  • konwerska, aneta
  • bryja, artur
  • kranc, wiesława
  • jankowski, maurycy
  • nawrocki, mariusz j.
  • kocherova, ievgeniia
  • celichowski, piotr
  • borowiec, blanka
  • popis, małgorzata
  • budna-tukan, joanna
  • antosik, paweł
  • bukowska, dorota
  • brussow, klaus p.
  • pawelczyk, leszek
  • bruska, małgorzata
  • And 3 more
Publication Date
Dec 26, 2018
Source
MDPI
Keywords
Language
English
License
Green
External links

Abstract

0.05) belonging to four ontological groups: regulation of cell proliferation (GO:0042127), regulation of cell migration (GO:0030334), and regulation of programmed cell death (GO:0043067) that can be used together as proliferation, migration or apoptosis markers. We have identified several genes of porcine oocytes (ID2, VEGFA, BTG2, ESR1, CCND2, EDNRA, ANGPTL4, TGFBR3, GJA1, LAMA2, KIT, TPM1, VCP, GRID2, MEF2C, RPS3A, PLD1, BTG3, CD47, MITF), whose expression after in vitro maturation (IVM) is downregulated with different degrees. Our results may be helpful in further elucidating the molecular basis and functional significance of a number of gene markers associated with the processes of migration, proliferation and angiogenesis occurring in COCs.

Report this publication

Statistics

Seen <100 times