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Unintended Consequences of not Specifying Exclusionary Illnesses for Systemic Exertion Intolerance Disease.

Authors
  • Jason, Leonard A1
  • Sunnquist, Madison2
  • Kot, Bobby3
  • Brown, Abigail4
  • 1 Center for Community Research, DePaul University, Chicago, IL 60614, USA. [email protected]
  • 2 Center for Community Research, DePaul University, Chicago, IL 60614, USA. [email protected]
  • 3 Center for Community Research, DePaul University, Chicago, IL 60614, USA. [email protected]
  • 4 Center for Community Research, DePaul University, Chicago, IL 60614, USA. [email protected]
Type
Published Article
Journal
Diagnostics
Publisher
MDPI AG
Publication Date
Jun 23, 2015
Volume
5
Issue
2
Pages
272–286
Identifiers
DOI: 10.3390/diagnostics5020272
PMID: 26854153
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

The Institute of Medicine recently proposed a new case definition for chronic fatigue syndrome (CFS), as well as a new name, Systemic Exertion Intolerance Disease (SEID). Contrary to the Fukuda et al.'s CFS case definition, there are few exclusionary illnesses specified for this new SEID case definition. The current study explored this decision regarding exclusionary illnesses using the SEID criteria with four distinct data sets involving patients who had been identified as having CFS, as well as healthy controls, community controls, and other illness groups. The findings indicate that many individuals from major depressive disorder illness groups as well as other medical illnesses were categorized as having SEID. The past CFS Fukuda et al. prevalence rate in a community based sample of 0.42 increased by 2.8 times with the new SEID criteria. The consequences for this broadening of the case definition are discussed.

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