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Understanding and treating cytopenia through mathematical modeling.

Authors
  • Lei, Jinzhi
  • Mackey, Michael C
Type
Published Article
Journal
Advances in experimental medicine and biology
Publication Date
Jan 01, 2014
Volume
844
Pages
279–302
Identifiers
DOI: 10.1007/978-1-4939-2095-2_14
PMID: 25480647
Source
Medline
License
Unknown

Abstract

Here, we briefly review how the study of dynamic hematological diseases with mathematical modeling tools has led to a better understanding of the origin of some types of neutropenia and thrombocytopenia and to improved treatment strategies. In addition, we have briefly discussed how these models suggest improved ways to minimize and/or treat cytopenia induced by chemotherapy.

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