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Understanding gastrointestinal perfusion in critical care: so near, and yet so far.

Authors
  • Ackland, G
  • Grocott, M P
  • Mythen, M G
Type
Published Article
Journal
Critical care (London, England)
Publication Date
Jan 01, 2000
Volume
4
Issue
5
Pages
269–281
Identifiers
PMID: 11094506
Source
Medline
License
Unknown

Abstract

An association between abnormal gastrointestinal perfusion and critical illness has been suggested for a number of years. Much of the data to support this idea comes from studies using gastric tonometry. Although an attractive technology, the interpretation of tonometry data is complex. Furthermore, current understanding of the physiology of gastrointestinal perfusion in health and disease is incomplete. This review considers critically the striking clinical data and basic physiological investigations that support a key role for gastrointestinal hypoperfusion in initiating and/or perpetuating critical disease.

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