Affordable Access

Underestimation of meningococci in tonsillar tissue by nasopharyngeal swabbing.

Authors
  • Sim, R J
  • Harrison, M M
  • Moxon, E R
  • Tang, C M
Type
Published Article
Journal
Lancet (London, England)
Publication Date
Nov 11, 2000
Volume
356
Issue
9242
Pages
1653–1654
Identifiers
PMID: 11089827
Source
Medline
License
Unknown

Abstract

The relation between carriage of Neisseria meningitidis and progression to invasive disease is not fully understood. We assessed the rate of N. meningitidis carriage by conventional swabbing and immunohistochemistry in patients undergoing tonsillectomy. Swabbing detected only a quarter of carriers, and bacteria were identified beneath the mucosal surface in tonsillar tissue by immunochemical testing. Our results indicate that N. meningitidis is more widespread in the population than previously thought, and have broad implications for disease prevention and cure.

Report this publication

Statistics

Seen <100 times