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UNBS1450 from Calotropis procera as a regulator of signaling pathways involved in proliferation and cell death

Authors
Type
Published Article
Journal
Biochemical Pharmacology
Publisher
Elsevier
Publication Date
Jul 23, 2009
Volume
78
Issue
1
Pages
10–10
Identifiers
DOI: 10.1016/j.bcp.2009.01.018
Source
LBMCC
Keywords
License
Green

Abstract

Despite significant progress in oncology therapeutics in the last decades, the urge to discover and to develop new, alternative or synergistic anti-cancer agents still remains. For centuries it has been known that the coarse shrub Calotropis procera is a very promising source of ascaricidal, schizonticidal, anti-bacterial, anthelmintic, insecticidal, anti-inflammatory, anti-diarrhoeal, larvicidal and cytotoxic chemicals. Different compounds like norditerpenic esters, organic carbonates, the cysteine protease procerain, alkaloids, …

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