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Ultrastructure of convoluted proximal tubule of kidney mice before and after X-ray exposure.

Authors
  • Enokihara, M M
  • Pacheco, I P
  • Segreto, H R
Type
Published Article
Journal
Revista paulista de medicina
Publication Date
Jan 01, 1993
Volume
111
Issue
3
Pages
403–406
Identifiers
PMID: 8108633
Source
Medline
License
Unknown

Abstract

Ultrastructural initial changes study of convoluted proximal tubule after single dose of 154.8 mC/kg (600R), X-ray whole body radiation was performed in 12 C57BL mice. Twenty-four hours later, mitochondria evidenced proeminent changes such as cristolyses, dilatation and vacuolization. Within 72 hours, heterochromatin nuclei increased and vanished 144 hours after X-ray exposure. Such findings suggest that recovery probably happened because convoluted proximal tubules take place, regeneration occurs in a slow rate.

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